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AcclaimPolarAdvantage(PAC16):Rugged極性鍵合反相柱,用于分析極性和AcclaimPolarAdvantage(PAC16):Rugged極性鍵合反相柱,用于分析極性和 Thermo Fisher

AcclaimPolarAdvantage(PAC16):Rugged極性鍵合反相柱,用于分析極性和AcclaimPolarAdvantage(PAC16):Rugged極性鍵合反相柱,用于分析極性和

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 Acclaim PolarAdvantage: Rugged 極性鍵合反相柱,用于分析極性和非極性成分
  The Acclaim® PolarAdvantage (PA) 柱擁有專利的鍵合相技術(shù),極性磺胺基團(tuán)鍵合到硅膠基質(zhì)表面,這種特性加強(qiáng)了柱子水解穩(wěn)定性,能同時(shí)保留極性和非極性分析物。該色譜柱兼容100%水相,同時(shí)兼有反相柱特點(diǎn),與LC-MS兼容。
 

Sulfonamide-Embedded Reversed-Phase Columns for Separating Polar Compounds

Acclaim® Polar Advantage (PA C16) columns feature a patented bonding chemistry that incorporates a polar sulfonamide group near the surface of the silica particle. This unique chemistry provides good hydrolytic stability and allows a single column to resolve a wide variety of polar and nonpolar analytes. The Acclaim PA is compatible with 100% aqueous mobile phases and supports LC/MS analysis.

  • Low silanol activity for excellent peak shape with basic compounds
  • Novel polar-embedded column chemistry
  • Compatible with 0–100% organic solvent mobile phases
  • High selectivity for hydrophobic aromatic compounds
  • Wide range of applications

Conventional C18 phases are not compatible with highly aqueous mobile phases, due to dewetting. The Acclaim PA column by design has a mildly hydrophilic surface, which remains in contact with aqueous-only mobile phases, negating the problems of dewetting common with conventional reversed-phase columns.

Acclaim PA columns are available both in 3 and 5 μm particle sizes and 4.6, 3.0, and 2.1 mm diameters, with an average pore diameter of 120 Å. Acclaim PA is also available in 2.2µm RSLC format (see Acclaim Rapid Separation LC (RSLC) Columns section for more details). Acclaim PA may be used for LC/MS applications. 

Applications

The Acclaim PA column can be used in a wide range of applications in pharmaceutical, environmental, food testing, and product-quality testing. These columns also give efficient separations with good peak shapes for compounds of life science (nucleic acid and bases) and pharmaceutical interest (sulfonamides) using highly aqueous mobile phases.

Acclaim PolarAdvantage: Rugged Polar-Embedded Reversed-Phase Columns for the Analysis of Polar and Nonpolar Compounds  Specifications
Surface coverage 2.7 mmol/m2
End-capped Yes
Metal impurity (Na, Fe, Al) <10.0 ppm Total Metal
<3.0 ppm Individual Metal
Pore volume 1.0 mL/g
Average pore diameter 120 Å
Surface area 300 m2/g
pH range 2–8
Temperature <60 °C
Starting material Ultrapure silica
Particle size 3 and 5 µ
Particle shape Spherical
Particle size distribution (40/90) <1.3
Total carbon content 0.17


訂購信息:
Analytical Columns Part No.
Acclaim PA, 3 µm Analytical (2.1 x 100 mm) 061316
Acclaim PA, 3 µm Analytical (2.1 x 150 mm) 061317
Acclaim 120, PA, 3µm Analytical (2.1 x 250mm) 076215
Acclaim PA, 3µm Analytical, (3.0 x 50mm) 068972
Acclaim 120, PA, 3µm Analytical (3.0 x 100mm) 076214
Acclaim PA, 3 µm Analyitcal (3.0 x 150 mm) 063693
Acclaim PA, 3 µm, Analytical, (3.0 x 250 mm) 070079
Acclaim PA, 3 µm Analytical (4.6 x 150 mm) 061318
Acclaim 120, PA, 3µm Analytical (4.6 x 100mm) 076216
Acclaim PA, 5 µm Analytical (4.6 x 50 mm) 061319
Acclaim PA, 5 µm Analytical (4.6 x 150 mm) 061320
Acclaim PA, 5 µm Analytical (4.6 x 250 mm) 061321
   
Guard Columns Part No.
Acclaim PA, 5µm,2mm Guard Cartridges, (2.1 x 10mm), 2 ea;
requires holder 069580
069691
Acclaim PA, 5µm Guard Cartridges (3 x 10mm), 2ea;
requires holder 069580
071983
Acclaim PA, 5 µm Guard Cartridges, (4.6 x 10 mm), 2 ea (use V-2 Holder) 069698
Acclaim SST Guard Cartridge Holder V-2 069580
Acclaim Guard Kit (Holder and coupler) V-2 069707
Guard to Analytical Column Coupler V-2 074188
   
Acclaim RSLC PA Analytical Columns Part No.
Acclaim RSLC PA, 3 µm Analytical (3.0 x 33 mm) 066274
Acclaim PA, 3µm Analytical, (3.0 x 50mm) 068972
Acclaim RSLC PA, 3 µm Analytical (3.0 x 75 mm) 066275
Acclaim PA, 3 µm Analyitcal (3.0 x 150 mm) 063693
Acclaim RSLC PA, 2.2µm, 2.1 x 50 mm 072622
Acclaim RSLC PA, 2.2µm, 2.1 x 30 mm 072621
Acclaim RSLC PA, 2.2µm, 2.1 x 100 mm 072623
Acclaim RSLC PA, 2.2µm, 2.1 x 150 mm 072624
Acclaim RSLC PA, 2.2µm Analytical (2.1 x 250mm) 074813
Acclaim RSLC PA, 2.2µm, 3 x 30mm 072625
Acclaim RSLC PA, 2.2µm, 3 x 100mm 072627
Acclaim RSLC PA, 2.2µm, 3 x 50mm 072626

Analytical Columns
Acclaim PA, 3μm Analytical (2.1 × 50 mm).................................... 063174
Acclaim PA, 3μm Analytical (2.1 × 100 mm)................................... 061316
Acclaim PA, 3μm Analytical (2.1 × 150 mm)................................... 061317
Acclaim PA, 3μm Analytical (3 × 150 mm)..................................... 063693
Acclaim PA, 3μm Analytical (4.6 × 150 mm)................................... 061318
Acclaim PA, 5μm Analytical (4.6 × 50 mm).................................... 061319
Acclaim PA, 5μm Analytical (4.6 × 150 mm)................................... 061320
Acclaim PA, 5μm Analytical (4.6 × 250 mm)................................... 06132
Guard Columns
Acclaim PA, 5μm Guard Cartridges (2.0x10 mm), 2 each......................... 061331
Acclaim PA, 5μm Guard Cartridges (4.3x10 mm), 2 each......................... 061332
Guard cartridges require holder.
SST Guard Cartridge Holder.................................................... 059456
Guard to Analytical Column Coupler............................................ 059457
Guard Kit (Holder and Coupler)................................................ 059526
Micro and Nano Columns
75 μm i.d. × 5 cm, Acclaim PA, 3 μm........................................ 162244
300 μm i.d. × 5 cm, Acclaim PA, 3 μm....................................... 162242
300 μm i.d. × 15 cm, Acclaim PA, 3 μm...................................... 162243
1.0 mm i.d. × 5 cm, Acclaim PA, 3 μm........................................ 162240
1.0 mm i.d. × 15 cm, Acclaim PA, 3 μm....................................... 162241
75 μm i.d. × 5 cm, Acclaim PA, 5 μm........................................ 162252
75 μm i.d. × 15 cm, Acclaim PA, 5 μm....................................... 162253
75 μm i.d. × 25 cm, Acclaim PA, 5 μm....................................... 162254
300 μm i.d. × 5 cm, Acclaim PA, 5 μm....................................... 162249
300 μm i.d. × 15 cm, Acclaim PA, 5 μm...................................... 162250
1.0 mm i.d. × 5 cm, Acclaim PA, 5 μm........................................ 162246
1.0 mm i.d. × 15 cm, Acclaim PA, 5 μm....................................... 162247
1.0 mm i.d. × 15 cm, Acclaim PA, 5 μm....................................... 162247
1.0 mm i.d. × 25 cm, Acclaim PA, 5 μm....................................... 162248
Micro and Nano Precolumns
300 μm i.d. × 5 mm, Acclaim PA, 5 μm (set of 5 cartridges)................. 162302
500 μm i.d. × 5 mm, Acclaim PA, 5 μm (set of 5 cartridges)................. 162336
500 μm i.d. × 15 mm, Acclaim PA, 5 μm (set of 5 cartridges)................ 162337
800 μm i.d. × 5 mm, Acclaim PA, 5 μm (set of 5 cartridges)................. 162335
1.0 mm i.d. × 5 mm, Acclaim PA, 5 μm (set of 5 cartridges).................. 162333
1.0 mm i.d. × 15 mm, Acclaim PA, 5 μm (set of 5 cartridges)................. 162334
75 μm i.d. × 15 cm, Acclaim PA, 3 μm....................................... 162245

應(yīng)用譜圖:

Fat-soluble vitamins and carotenoids in a vitamin tablet.

 

Loratidine and pseudo-ephedrine in a time-release tablet.

 

LC separation of nitrosamines, as specified in EPA 8270.

 

 

 

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